Pregabalin Capsules
Pregabalin 300mg Capsules- NerviAsh 300 available in Australia, USA, UK, Philippines, New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, Sydney, Melbourne, Brisbane, Perth, Adelaide, Canberra, London, Birmingham, Manchester, Liverpool, Leeds, Glasgow, Edinburgh, Quezon City, Manila, Davao City , San Jose, Sydney, Melbourne, Brisbane for hospitals, distributors, and export buyers. GMP-certified supplied across world with global shipping.
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Product Introduction
Brand Name: NERVIASH
Generic Name: Pregabalin
Strength: 300 mg
Dosage Form: Capsules (For Oral Use Only)
Storage: Store below 30Β°C. Protect from moisture. Keep out of reach of children.
NERVIASH 300 mg Capsules contain Pregabalin IP, a gamma-aminobutyric acid (GABA) analogue with proven efficacy in the management of neuropathic pain and certain neurological disorders. Pregabalin modulates nerve signal transmission, helping reduce pain signals and neuronal hyperexcitability.
NERVIASH 300 mg is prescribed under medical supervision for the treatment of neuropathic pain, epilepsy (as adjunctive therapy), and other related conditions. Dosage and duration are individualized based on patient response and tolerability.
Indications / Uses
NERVIASH 300 mg Capsules are indicated for:
Management of neuropathic pain, including:
Diabetic peripheral neuropathy
Postherpetic neuralgia
Neuropathic pain associated with spinal cord injury
Adjunctive therapy for partial seizures in adults
Fibromyalgia
Generalized Anxiety Disorder (GAD) (where approved and as prescribed by the physician)
Benefits
Effective pain relief: Reduces neuropathic pain intensity
Rapid onset of action: Provides symptom relief early in therapy
Improves quality of life: Enhances sleep and daily functioning
Reduces neuronal hyperexcitability: Controls abnormal nerve signaling
Convenient oral capsule: Easy to administer
Mechanism of Action
Pregabalin does not act directly on GABA receptors but modulates calcium channel activity in the central nervous system.
Mechanism of Action
Calcium Channel Modulation:
Binds to the Ξ±2Ξ΄ subunit of voltage-gated calcium channels in the CNS.
Reduction of Neurotransmitter Release:
Decreases the release of excitatory neurotransmitters such as glutamate, norepinephrine, and substance P.
Pain and Seizure Control:
Reduces neuronal excitability, leading to relief from neuropathic pain and seizure stabilization.
Anxiolytic Effect:
Modulates synaptic transmission involved in anxiety pathways.
Side Effects
Common side effects:
Dizziness
Somnolence (sleepiness)
Dry mouth
Blurred vision
Weight gain
Peripheral edema
Difficulty concentrating
Less common but serious side effects:
Allergic reactions (angioedema, facial swelling)
Suicidal thoughts or behavior
Severe dizziness or loss of consciousness
Vision changes
Muscle pain with fever (possible rhabdomyolysis)
Seek immediate medical attention if you experience facial swelling, breathing difficulty, severe rash, mood changes, or suicidal thoughts.
Safety Advice
Alcohol:
Avoid alcohol, as it may increase dizziness, drowsiness, and impaired coordination.
Pregnancy & Breastfeeding:
Use only if clearly needed and prescribed by a physician.
Potential risk to the fetus; benefit-risk assessment required.
Pregabalin is excreted in breast milk; breastfeeding is not recommended unless advised by the doctor.
Kidney:
Dose adjustment is required in patients with renal impairment.
Other Medical Conditions:
Inform your doctor if you have:
Kidney disease
Heart failure
History of substance abuse
Depression or mood disorders
Dosage & Administration
Take NERVIASH 300 mg Capsules exactly as prescribed by your physician.
Can be taken with or without food.
Swallow the capsule whole with water; do not crush or chew.
Do not stop abruptly; tapering is required to prevent withdrawal symptoms.
Dosage depends on indication, patient response, and renal function.
Medical Supervision & Monitoring
Use of NERVIASH 300 mg should be under strict medical supervision.
Monitoring may include:
Assessment of pain or seizure control
Renal function tests
Monitoring for mood changes or suicidal ideation
Evaluation for weight gain and edema
Prescribe the l