Letrozole 2.5mg Tablets
Letrozole 2.5mg Tablets available in Australia, USA, UK, Philippines, New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, Sydney, Melbourne, Brisbane, Perth, Adelaide, Canberra, London, Birmingham, Manchester, Liverpool, Leeds, Glasgow, Edinburgh, Quezon City, Manila, Davao City , San Jose, Sydney, Melbourne, Brisbane for hospitals, distributors, and export buyers. GMP-certified supplied across world with global shipping.
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Product Introduction
Brand Name: Letrojust 2.5mg tablets
Salt Composition: Letrozole (2.5mg)
Dosage Form: Tablet (For Oral Use Only)
Storage: Store below 30°C. Protect from moisture and direct sunlight. Keep out of reach of children.
Description
Letrozole 2.5mg Tablets is an oral aromatase inhibitor used in the treatment of hormone receptor-positive breast cancer, primarily in postmenopausal women. It helps reduce estrogen production in the body, thereby slowing or stopping the growth of estrogen-dependent cancer cells.
Letrozole is also used off-label as a fertility aid to induce ovulation in women who have ovulatory dysfunction, including those with polycystic ovary syndrome (PCOS).
Uses of Letrozole 2.5mg Tablets
Treatment of hormone receptor-positive breast cancer in postmenopausal women
Adjuvant therapy after surgery or chemotherapy to prevent recurrence
Management of advanced or metastatic breast cancer
Ovulation induction in women with PCOS or unexplained infertility (off-label)
Benefits
Effectively lowers estrogen levels, controlling hormone-dependent tumor growth
Reduces the risk of cancer recurrence after treatment
Enhances ovulation response in women with PCOS
Non-steroidal and generally well-tolerated
Suitable for long-term management under medical supervision
Mechanism of Action
Letrozole works by inhibiting the aromatase enzyme, which is responsible for converting androgens (such as testosterone) into estrogens in peripheral tissues.
By blocking this conversion, Letrozole reduces circulating estrogen levels, depriving estrogen-dependent cancer cells of the hormones they need to grow and multiply.
In fertility therapy, the temporary reduction in estrogen levels stimulates the pituitary gland to release more follicle-stimulating hormone (FSH), promoting follicular development and ovulation.
Side Effects
Common:
Hot flashes or flushing
Headache and fatigue
Joint or muscle pain (arthralgia, myalgia)
Nausea or mild dizziness
Less Common:
Bone loss or osteoporosis with long-term use
Mood changes or insomnia
Increased cholesterol levels
Headache or nausea
Less Common / Rare:
Mood changes or fatigue
Water retention or weight fluctuation
Pigmentation or rash at the application area
⚠️ Seek immediate medical attention if you experience signs of blood clots (leg pain, chest pain, sudden breathlessness), severe headache, or unusual vaginal bleeding.
Safety Advice
For external use only. Avoid contact with eyes, breasts, or broken skin.
Pregnancy & Breastfeeding: Contraindicated; discontinue immediately if pregnancy occurs.
Liver/Kidney Impairment: Use with caution under medical supervision.
Smoking: Avoid smoking to reduce the risk of cardiovascular complications.
Alcohol: Limit intake to maintain hormonal balance.
Driving/Machinery: Generally safe; avoid if experiencing dizziness or headache.
Administration Guidelines
Apply once daily at the same time each day, preferably on clean, dry, and intact skin of the arms, shoulders, or thighs.
Spread the gel evenly in a thin layer and allow it to dry for a few minutes before dressing.
Do not wash the application site for at least one hour after use.
Avoid applying near the breasts or genital area.
Follow the dosage and duration as prescribed by your physician.
Diet & Lifestyle Advice
Eat a balanced diet rich in calcium and vitamin D to maintain bone strength.
Engage in regular physical exercise (walking, yoga, strength training).
Avoid smoking and excessive alcohol consumption.
Practice stress-reduction techniques such as meditation or deep breathing.
Attend regular medical checkups, including breast and pelvic examinations, during long-term HRT.
