Janumet Tablets
Janumet Tablets Sitagliptin (50mg) + Metformin Hydrochloride (500mg / 1000mg) available in Australia, USA, UK, Philippines, New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, Sydney, Melbourne, Brisbane, Perth, Adelaide, Canberra, London, Birmingham, Manchester, Liverpool, Leeds, Glasgow, Edinburgh, Quezon City, Manila, Davao City , San Jose, Sydney, Melbourne, Brisbane for hospitals, distributors, and export buyers. GMP-certified supplied across world with global shipping.
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Sky High Medex
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Product Introduction
SALT COMPOSITION: Sitagliptin (50mg) + Metformin Hydrochloride (500mg / 1000mg)
Dosage Form: Tablet (For Oral Use Only)
Storage: Store below 30°C. Protect from moisture and direct sunlight. Keep out of reach of children.
Janumet Tablets combine two complementary antidiabetic agents—Sitagliptin, a DPP-4 inhibitor, and Metformin, a biguanide—to effectively manage blood glucose levels in adults with type 2 diabetes mellitus. This dual-action formulation enhances the body’s natural ability to regulate blood sugar levels both after and between meals. Sitagliptin increases incretin hormone activity, stimulating insulin release and reducing glucagon levels, while Metformin decreases hepatic glucose production and improves insulin sensitivity.
It is used as part of a comprehensive treatment plan including diet, exercise, and lifestyle modifications to achieve optimal glycemic control.
Uses of Janumet Tablets
Type 2 diabetes mellitus management
Improved glycemic control when diet and exercise alone are insufficient
Combination therapy alternative to separate Sitagliptin and Metformin tablets
Benefits of Janumet Tablets
Dual mechanism for effective blood sugar regulation
Reduces fasting and post-meal glucose levels
Low risk of hypoglycemia when used alone
Helps maintain stable HbA1c levels over time
Convenient single-tablet dosing for better adherence
Supports weight neutrality (unlike certain other diabetic drugs)
How Janumet Tablets Work
Janumet works by combining two mechanisms of action:
1. Sitagliptin (DPP-4 inhibitor):
Increases incretin levels (GLP-1 and GIP), which enhance insulin release in response to meals
Lowers glucagon secretion, reducing hepatic glucose production
2. Metformin (Biguanide):
Decreases glucose production in the liver
Improves insulin sensitivity in muscle and fat cells
Slows intestinal absorption of glucose
Together, these actions provide comprehensive glucose control and reduce long-term diabetic complications.
Side Effects
Common side effects:
Nausea or stomach upset
Diarrhea
Headache
Weakness or fatigue
Low blood sugar (especially if used with sulfonylureas or insulin)
Serious but rare side effects:
Lactic acidosis (severe weakness, abdominal pain, irregular heartbeat)
Pancreatitis (severe upper abdominal pain)
Kidney impairment
Allergic reactions (rash, swelling, difficulty breathing)
Seek immediate medical help if severe side effects occur.
Safety Advice
Alcohol: Avoid excessive alcohol to minimize risk of lactic acidosis.
Pregnancy & Breastfeeding: Use only if prescribed by a healthcare provider. Not recommended during pregnancy unless clearly needed.
Kidney/Liver: Contraindicated in patients with severe renal or hepatic impairment. Regular monitoring is advised.
Diet & Exercise: Maintain a balanced diet and regular exercise regimen to maximize therapeutic benefit.
Medical Supervision:
Take exactly as prescribed by a healthcare professional. Do not skip or double doses. Monitor blood sugar levels regularly.
